Laura Peeters

100 | Chapter 5 RESULTS Participant characteristics Participant characteristics are described in Table 1. Participants who reported pain at time of the measurement, had mainly (chronic) shoulder pain which did not have major impact on their mobility in daily life. None of the participants used medication described as affecting SMA, except for one participant who used Mestinon. The 6-year old, type 2 SMA participant is not included in the table. His Vignos scale was 9, Brooke scale 1 and he had no scoliosis. Three participants with SMA were not able to sit unsupported and perform tasks at the same time, and were excluded from the kinematic and muscle activity analysis. They all had SMA type 2, spinal fusion surgery and scored 3, 5 and 6 on the Brooke scale. One of these subjects wore a trunk brace, others did not. Healthy controls SMA patients n median IQR n median IQR Age [years] 15 18.1[14.4-20.4] 16 43.5 [25.5-57.2] Gender [male/female] 7 / 8 11 / 5 Weight [kg] 15 60.0[51.1-66.5] 16 74.5 [56.6-88.1] Height [cm] 14 170.5[166.0-174.0] 15 176.0 [167.0-178.8] Sitting height [cm] 15 64.5[62.1-67.5] 14 63.0 [52.0-69.0] Pain at time of participation [n] 0 5 Type of SMA [type 2/type3] 5 / 11 Age of diagnosis [years] 16 3.5 [2-16] Wheelchair confinement [n] 14 Scoliosis [n] 0 9 Spinal fusion surgery [n] 0 6 Vignos lower extremity scale 1 2 9 [n] 1 1 14 Brooke upper extremity scale 1 2 3 4 5 6 [n] 3 3 8 0 1 1 Table 1 Participant characteristics