Hans van den Heuvel

Table 1. The ten-question preeclampsia symptom checklist in the telemonitoring platform, to be answered with Yes or No buttons. Do you have headaches? Do you have visual problems? Do you have a tight, band-like feeling around the upper stomach? Do you experience severe upper abdominal pain? Do your fingers feel numb? Do you feel nauseous? Do you have ankle, hand or face swelling? Do you have contractions? Do you have vaginal fluid loss? Do you have vaginal bleeding? Outcomes and data collection Primary outcomes were healthcare consumption and user experiences of the digital telemonitoring platform. Secondary outcomes were maternal and neonatal perinatal outcomes. For healthcare consumption, the number of antenatal visits, ultrasounds for fetal assessment, blood and urinary analysis, medication use and admissions were extracted fromparticipants’ hospital system. For user experiences, SAFE@HOME participants were invited to answer an online survey at 36 weeks of gestation with 10 statements regarding their experiences with the platform on a 5-point Likert scale. Derived from the Luscii webportal, the start, duration and frequency blood pressure and symptom monitoring, as well as number of alerts and raised readings were recorded. For maternal and perinatal outcome, pregnancy and delivery data were recorded and used to compare both groups. Risk factors for preeclampsia in each group and other maternal characteristics were collected at baseline from hospital records. Chronic hypertension, gestational hypertension, preeclampsia and eclampsia were defined according to ISSHP criteria. 15 Statistical analyses Given the exploratory nature of this study, no formal sample size calculation was performed. Continuous outcome variables were represented as means with standard deviations or, if skewed, medians with interquartile ranges (IQR), and were compared by the Student’s t-test or Mann-Whitney-U test. Categorical outcome variables were compared between groups by the chi-square or Fisher’s exact test. P-values below 0.05 were considered as statistically significant. Statistical analysis was performed with IBM SPSS version 25. CHAPTER 5 72