Mieke Bus

56 Chapter 4 Results Figure 2 shows OCT images of a healthy ureter obtained during URS of a normal looking ureter. Urothelium, basement membrane, lamina propria and muscularis are clearly visible. Figure 2: OCT scan of a healthy ureter, measured during URS of patient number 2 in the contra lateral ureter. A) Individual OCT scans extracted from the volumetric OCT dataset as shown in B. Inset shows a magnification indicating the three different layers, urothelium (#), lamina propria (*) and muscularis ($) of a normal ureter. B) The automatic pullback system scans across a trajectory of 52 mm along the probe in approximately 5.2 seconds, producing a 520-frame dataset. This results in a total scanned cylindrical volume of 52 (length) by 10 mm (diameter). Reconstruction software from Amira (Visage Imaging GmbH, Berlin, Germany) was used to visualize a complete dataset of the ureter. Eight consecutive patients (Table 1) underwent ureterorenoscopy (URS) plus biopsies for UTUC combined with OCT, followed by nephroureterectomy.