Mieke Bus

58 Chapter 4 Figure 4: A) Intra-operative in-vivo cross-sectional OCT images of the ureter with a protrusion into the lumen (left, #arrow). Individual tissue layers can be identifiedwith protrusion (arrow).The basal membrane is visible as a thin dark line under the protrusion (#), suggesting a non-invasive tumor. Corresponding histology (right) showed a TaG1-2 urothelial cancer. B) In normal ureter wall (left), individual tissue layers can be identified as urothelial layer (*) and basement membrane (#). Corresponding histology is shown right. C) 3D pullback of the OCT, built from 520 individual cross-sectional images over a length of 5.2 cm. Suspected tumor regions are segmented given a green hue.