Stephanie van Hoppe

191 Acknowledgements Kimberley Heinhuis, Hans te Poele, Thea Eggenhuizen, Jan Schellens, Sven de Krou, Onno Bleijerveld, Liesbeth Hoekman, Maarten Altelaar, Evelien van Kampen, Aurelia de Vries Schultink, Hedvig Arnamo, Marit Vermunt, Ignace Roseboom, Jonathan Knikman, Jorn Mulder, Julie Janssen, Karen de Jong, Laura Molenaar - Kuijsten, Lisa van der Heijden, Luka Verrest, Maaike Bruin, Maarten van Eijk, Nikki Ijzerman, Paniz Heydari, Rene Boosman, Roel van Gijn, Sanne Huijberts, Semra Palic, Thomas Dorlo, Merel van Nuland, Steffie Groenland, Linda Henricks, Willeke Ros, Lotte van Andel. Mark (dG), thank you nice discussions and conversations we’ve had. It’s always nice to discuss science with you! Mark (vB) thank you for the discussions concerning the osimertinib project. Onno , you’re always filled with joy and I enjoyed our conversations during my time at H3. Liesbeth , it was nice having so many conversations with you. Time flew by way faster than it was supposed to those times! A big thank you to all the other colleagues from the NKI that I had good conversations and/or discussions with. There are so many of you but I will try to thank you all: Elma Mons, Jeroen Hendrikx, Koen Flach, Christ Leemans, Ewald van Dyk, Peter Remeijer, Andrea Murachelli, Patti Lagerweij, Tom de Wit, Marijne Schijns, Antonio Sanchez, Joao Neto, Fernando Polo and Behzad Mombeini. Elma, thank you for all the nice discussions and your great insight into the world of chemistry, which is still quite foreign to me. I enjoyed the times together and look forward to your thesis! Peter , I am grateful for your advice you gave me concerning my PhD and career. This has helped me a lot! Jeroen , it was always great to talk to you about career aspects what to include in a thesis and science overall. A huge thank you to all my friends outside of academia or the NKI, who were so understanding every time I was either late or had to cancel an appointment because of an experiment or deadline. Thank you all for your support and for listening to me talk about science. I’m super lucky to have friends like you! I wish to especially thank Jasmin Hettich, Sarah van Leeuwen, Valeria Bella, Barbara van der Hoeven, Emiel Ordelmans, Mindy Au, Marloes Vogel, Sheila Clement, Nicole Bo ë tius, Melle Holwerda and Ioana Niculescu for your support! And a thank you to G ü ls ü m Yalcin , who was able to translate my idea for the cover so well! Thank you for making me so happy with my cover! Tomy former colleagues at Cergentis: JanDekker, Max vanMin, Erik Splinter, Harma Feitsma, Judith Bergboer, Martijn Kelder, Allan La, Petra Klous, Mehmet Yilmaz, Irina Sergeeva, Elaine Wong, Melinda Aprelia, Joost Swennenhuis, Agata Rakszewska, Cheryl Dambrot and Wietske Stevens : thank you for your understanding and support during the final phase of writing this thesis while I was working there. It meant the world to me and I had a great time working with you all!