Stephanie van Hoppe

© Stéphanie Sigrid van Hoppe, Amsterdam, 2019. All rights reserved. ISBN 978-94-6375-554-2 Cover by GülsümYalcin Layout by Jos Hendrix Printed by Ridderprint BV, www.ridderprint.nl The research described in this thesis was performed at the Divisions of Molecular Oncology and Pharmacology of the Netherlands Cancer Institute, Amsterdam, The Netherlands. Printing of this thesis was financially supported by the Onderzoeksschool Oncologie Amsterdam.