Stephanie van Hoppe

2 Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-gp/ABCB1) transport afatinib and restrict its oral availability and brain accumulation Stéphanie van Hoppe 1 , Rolf W. Sparidans 2 , Els Wagenaar 1 , Jos H. Beijnen 2 and Alfred H. Schinkel 1 1 Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam 2 Section of Pharmacoepidemiology & Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht Pharmacol Res. 2017 Jun;120:43-50.