Stephanie van Hoppe

3 Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (Breast Cancer Resistance Protein) Stéphanie van Hoppe 1 , Amer Jamalpoor 1 , Gert-Jan Rood 2 , Els Wagenaar 1 , Rolf W. Sparidans 2 , Jos H. Beijnen 1,2 , Alfred H. Schinkel 1 1 Division of Molecular Pharmacology, The Netherlands Cancer Institute, Amsterdam 2 Section of Pharmacoepidemiology & Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Pharmacol Res . 2019 Aug;146:104297.