111 B-cell repopulation after rituximab in rheumatoid arthritis Figure S3 | Results excluding imputed data on depletion and repopulation A-C) Boxplot showing the changes in DAS28-score between month 1 (A) or month 3 (B) post-treatment and baseline in early or late depleting patients and (C) the changes in DAS28score between the month 6 and month 12 after treatment in early or late repopulation patients. Boxplots show the median and 25th and 75th interquartile and error bars show the range. Single data points are depicted in grey (** p ≤ 0.01, using unpaired t-test in B and C). D) Barplot showing the correlation between anti-drugs antibodies (ADA) development and repopulation within 12 months of treatment. 5
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