128 CHAPTER 6 Figure 3| Behaviour of BCRh clones in RA-risk individuals over time Dot plots of (A-B) the number and impact of dominant BCRh clones in the PRAIRI study. (C-D) the number and impact of dominant BCRh clones in the DOMINO study (E-F) Line plots of the number of dominant BCRh clones over time in the PRAIRI and DOMINO studies. (G-H) percentage of overlapping top 25 BCRh clones in comparison with the screening visit per patient for the PRAIRI study (n=35) and the baseline visit for the DOMINO study (n=10) is shown. Data are presented as median and interquartile range.
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