Anne Musters

17 General introduction and outline 14 Bemis EA, Demoruelle MK, Seifert JA, Polinski KJ, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, ODell JR, Keating RM, Deane KD, Holers VM, Norris JM. 2021; Factors associated with progression to inflammatory arthritis in first-degree relatives of individuals with RA following autoantibody positive screening in a non-clinical setting. Ann Rheum Dis. 80(2):154–61. 15 Nielen MM, van Schaardenburg D, Reesink HW, Twisk JW, van de Stadt RJ, van der Horst-Bruinsma IE, de Gast T, Habibuw MR, Vandenbroucke JP, Dijkmans BA. 2004; Increased levels of C-reactive protein in serum from blood donors before the onset of rheumatoid arthritis. Arthritis Rheum. 50(8):2423–7. 16 Rantapää-Dahlqvist S, de Jong B a W, Berglin E, Hallmans G, Wadell G, Stenlund H, Sundin U, van Venrooij WJ. 2003; Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis Rheum. 48(10):2741–9. 17 Burgers L, van Steenbergen HW, ten Brinck RM, Huizinga T, van der Helm-van Mil AHM. 2017; Differences in the symptomatic phase preceding ACPA-positive and ACPA-negative RA: a longitudinal study in arthralgia during progression to clinical arthritis. Ann Rheum Dis. 76:1751–4. 18 Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham III CO, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JMW, Hobbs K, Huizinga TWJ, Kavanaugh A, et al. 2010; 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 62(9):2569–81. 19 Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, et al. 2014; Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 506(7488):376–81. 20 Kruglyak L. 2008; The road to genome-wide association studies. Nat Rev Genet. 9(4):314–8. 21 Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA. 2009; Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A. 106(23):9362–7. 22 Hu X, Kim H, Stahl E, Plenge R, Daly M, Raychaudhuri S. 2011; Integrating autoimmune risk loci with gene-expression data identifies specific pathogenic immune cell subsets. Am J Hum Genet. 89(4):496–506. 23 Yarwood A, Han B, Raychaudhuri S, Bowes J, Lunt M, Pappas DA, Kremer J, Greenberg JD, Plenge R, Rheumatoid Arthritis Consortium International (RACI), Worthington J, Barton A, Eyre S. 2015; A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk. Ann Rheum Dis. 74(1):170–6. 24 Kremer JM, Westhovens R, Leon M, Giorgio E Di, Alten R, Steinfeld S, Russell A, Dougados M, Emery P, Nuamah IF, Williams GR, Becker J-C, Hagerty DT, Moreland LW. 2003; Treatment of rheumatoid arthritis by elective inhibition of T-cell activation with fusion protein CTLA4Ig. N Engl J Med. 349(20):1907–15. 25 de Hair M, van de Sande MVD, Ramwadhdoebe T, Hansson M, Landewé R, van der Leij C, Maas M, Serre G, van Schaardenburg D, Klareskog L, Gerlag D, van Baarsen LGM, Tak P. 2014; Features of the synovium of individuals at risk of developing rheumatoid arthritis. Arthritis Rheumatol (Hoboken, N.j). 66:513–22. 26 Klarenbeek PL, de Hair MJH, Doorenspleet ME, van Schaik BDC, Esveldt REE, van de Sande MGH, Cantaert T, Gerlag DM, Baeten D, van Kampen a HC, Baas F, Tak PP, de Vries N. 2012; Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease. Ann Rheum Dis. 71(6):1088–93. 1

RkJQdWJsaXNoZXIy MTk4NDMw