Anne Musters

35 Synovitis is dominated by shared T-cell clones Supplementary data Figure S1 | Top-10, top-25 and top-100 most expanded TCRβ-clones when comparing samples from (A) within one joint (n=7), (B) two inflamed joints (n=9), (C) synovial tissue (ST) and synovial fluid (SF) (n=7), (D) ST and peripheral blood (PB) (n=10), and (E) SF and PB (n=10) (lines at mean and SD; testing using a one-way ANOVA). Figure S2 | Percentage of overlapping top-25 TCRβ-clones from the (A) suprapatellar (SP) region in comparison to various sizes of top pools of infrapatellar (IP) TCRβ-clones (n=14), (B) synovial tissue (ST) in comparison to various sizes of top pools of synovial fluid (SF) TCRβ-clones (n=9), (C) ST in comparison to various sizes of top pools of peripheral blood (PB) TCRβ-clones (n=19). 2

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