Anne Musters

Chapter 1 General introduction and outline 9
Chapter 2 In rheumatoid arthritis, synovitis at different inflammatory sites is dominated by shared but patient-specific T cell clone 23
Chapter 3 In rheumatoid arthritis inflamed joints share dominant patient-specific B-cell clones 41
Chapter 4 Prevention of rheumatoid arthritis: A systematic literature review of preventive strategies in at-risk individuals 59
Chapter 5 Sensitive B-cell receptor repertoire analysis shows repopulation correlates with clinical response to rituximab in rheumatoid arthritis 95
Chapter 6 Dynamics of the B cell receptor repertoire during the preclinical phase of rheumatoid arthritis: Longitudinal studies in untreated RA-risk individuals (DOMINO study) and the effects of rituximab treatment (PRAIRI study) 117
Chapter 7 General discussion and future perspectives 141
English summary 162
Nederlandse samenvatting 166
PhD portfolio 170
List of publications 174
Contributing authors 178
About the author 183
Dankwoord (Acknowledgements) 184

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