Albertine Donker

IRIDA: a Heterogeneous Disease 175 4 Hb a (g/dL) MCV a (fL) Ferritin a (μg/L) TSAT a (%) Hepcidin b (nmol/L) TSAT/hepcidin b (%/nM) Treatment p.Ala 736Val c 7.4 62 66 5.0 10 0.51 Iron po ineffective Iron iv partially effective 1 12.6 62 101 6.2 6.6 0.94 No treatment 1 11.9 68 32 6.1 7.8 0.78 Iron po sluggish respons No iron iv needed 1 11.1 74 20 6.1 5.2 1.2 No treatment 1 12 64 367 7.0 25 0.27 Iron po ineffective Iron iv partially effective np 13.9 86 60 13 2.3 5.8 No treatment np np np np np np np No treatment np 13.5 82 22 17 0.60 29 No treatment np 8.7 58 194 3.4 7.1 0.48 Blood Tx Iron po ineffective 0 11.8 86 280 17 6.4 2.7 Iron po ineffective Iron iv 0 np np np np np np No treatment 0 13.2 74 53 14 np np No treatment 0 10.6 86 151 14 1.3 11 No treatment 0 13.2 90 128 31 np np No treatment np 12.6 80 472 10 17 0.60 Iron po ineffective Iron iv partially effective 2 13.2 85 77 26 1.7 15 No treatment 1 15.1 91 27 13 <0.50 19 No treatment 1 14.7 84 22 19 <0.50 >38 No treatment np

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