Albertine Donker

IRIDA: a Heterogeneous Disease 179 4 Hb a (g/dL) MCV a (fL) Ferritin a (μg/L) TSAT a (%) Hepcidin b (nmol/L) TSAT/hepcidin b (%/nM) Treatment p.Ala 736Val c 8.7 56 4.0 4.0 1.4 2.9 Iron po not effective Iron iv partially effective 1 11.9 92 68 18 2.5 7.3 No treatment np 12.4 68 125 13 7.7 2.1 Iron po sluggish respons No iron iv needed 2 14.5 95 56 21 1.7 12 No treatment 1 16.1 85 98 38 1.7 23 No treatment 1 www.hepcidinanalysis.com . 5 The lower limit of reference range of TSAT/hepcidin ratio for adults is 1.7 %/nM for men, and 2.5 %/nM for premenopausal women. For children, no reference values are available until now, so we recommend using the reference values for premenopausal women. Abbreviations: Hb denotes hemoglobin, MCV, mean corpuscular volume, TSAT, transferrin saturation, F, female, M, male, iv, intravenous iron, po, per os, BloodTx, bloodtransfusion, np, not provided