Albertine Donker

Chapter 2 82 66. Jeney V. Clinical Impact and Cellular Mechanisms of Iron Overload-Associated Bone Loss. Frontiers in pharmacology. 2017;8:77. 67. YangQ, Jian J, AbramsonSB, HuangX. Inhibitory effects of iron on bone morphogenetic protein 2-induced osteoblastogenesis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2011;26(6):1188-1196. 68. Ishii KA, Fumoto T, Iwai K, et al. Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation. Nature medicine. 2009;15(3):259-266. 69. Tsay J, Yang Z, Ross FP, et al. Bone loss caused by iron overload in a murine model: importance of oxidative stress. Blood. 2010;116(14):2582- 2589. 70. Jiang Y, Yan Y, Wang X, Zhu G, Xu YJ. Hepcidin inhibition on the effect of osteogenesis in zebrafish. Biochemical and biophysical research communications. 2016;476(1):1-6. 71. Zoller H, Schaefer B, Glodny B. Iron- induced hypophosphatemia: an emerging complication. Current opinion in nephrology and hypertension. 2017;26(4):266-275. 72. Zhao GY, Zhao LP, He YF, et al. A comparison of the biological activities of human osteoblast hFOB1.19 between iron excess and iron deficiency. Biol Trace Elem Res. 2012;150(1- 3):487-495. 73. Toxqui L, Perez-Granados AM, Blanco-Rojo R, Wright I, de la Piedra C, Vaquero MP. Low iron status as a factor of increased bone resorption and effects of an iron and vitamin D-fortified skimmed milk on bone remodelling in young Spanish women. Eur J Nutr. 2014;53(2):441-448. 74. Wright I, Blanco-Rojo R, Fernandez MC, et al. Bone remodelling is reduced by recovery from iron-deficiency anaemia in premenopausal women. Journal of physiology and biochemistry. 2013;69(4):889-896. 75. Skordis N, Toumba M. Bone disease in thalassaemia major: recent advances in pathogenesis and clinical aspects. Pediatric endocrinology reviews : PER. 2011;8 Suppl 2:300-306. 76. Georgieff MK. Long-term brain and behavioral consequences of early iron deficiency. Nutrition reviews. 2011;69 Suppl 1:S43-48. 77. Georgieff MK. Iron assessment to protect the developing brain. The American journal of clinical nutrition. 2017;106(Suppl 6):1588s-1593s. 78. Hect JL, Daugherty AM, Hermez KM, Thomason ME. Developmental variation in regional brain iron and its relation to cognitive functions in childhood. Developmental cognitive neuroscience. 2018;34:18-26. 79. Tran PV, Carlson ES, Fretham SJ, Georgieff MK. Early-life iron deficiency anemia alters neurotrophic factor expression and hippocampal neuron differentiation inmale rats. The Journal of nutrition. 2008;138(12):2495- 2501. 80. Felt BT, Beard JL, Schallert T, et al. Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats. Behavioural brain research. 2006;171(2):261- 270. 81. Kaur D, Peng J, Chinta SJ, et al. Increased murine neonatal iron intake results in Parkinson-like neurodegeneration with age. Neurobiology of aging. 2007;28(6):907-913. 82. Berggren KL, Lu Z, Fox JA, Dudenhoeffer M, Agrawal S, Fox JH. Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington’s Disease Mice. Journal of Huntington’s disease. 2016;5(1):53- 63. 83. Hare DJ, Arora M, Jenkins NL, Finkelstein DI, Doble PA, Bush AI. Is early-life iron exposure critical in neurodegeneration? Nature reviews Neurology. 2015;11(9):536-544. 84. Lozoff B. Iron deficiency and child development. Food and nutrition bulletin. 2007;28(4 Suppl):S560-571. 85. Grantham-McGregor S, Ani C. A review of studies on the effect of iron deficiency on cognitive development in children. The Journal of nutrition. 2001;131(2s-2):649S-666S; discussion 666S-668S.