Albertine Donker

Chapter 3 96 Cells involved in iron homeostasis are duodenal enterocytes, hepatocytes, macrophages and erythroid precursors. To illustrate the description on pathophysiology for the different disorders, in Figure 1 we schematically present the function of the above-mentioned cells in iron homeostasis, and the proteins involved. Figure 1. Cells and proteins involved in iron homeostasis and heme synthesis