Sarah Bos

103 Efficacy of pro- and anticoagulant strategies in plasma 6 Figure 5. Absolute ETP levels from thrombomodulin modified thrombin generation testing in plasma of controls, and patients after PPPD prior to (-) and after (+) in vitro addition of prohemostatic agents. Start is after induction of anesthesia, end is at the end of surgery. Shown are medians with error bars indicating interquartile ranges, and the proportional difference in ETP upon addition of procoagulants. Statistical differences indicated are differences in proportional change in ETP upon addition of procoagulants between controls and patients. * p < 0.05 vs controls, ** P < 0.01 vs controls, *** P < 0.001 vs controls. FFP = fresh frozen plasma, PCC = prothrombin complex concentrate, rFVIIa = recombinant factor VIIa.