Kim Annink

141 The papez circuit and school-age outcome in HIE Supplemental Table 1: Continued Outcome measure Relative volume (%) or MB atrophy B-value R 2 value p-value Visual-spatial long-term memory, direct recall Hippocampus 67.1 0.133 0.022 MB atrophy -9.1 0.315 <0.001** Inferior temporal white matter 56.1 0.127 0.028 Middle temporal white matter 57.0 0.128 0.027 Superior frontal white matter 26.4 0.126 0.029 Lateral orbitofrontal cortex -42.3 0.161 0.014 Pars orbitalis cortex -90.8 0.132 0.027 Precentral cortex -24.6 0.110 0.045 Frontal cortex -159.7 0.200 0.006 Visual-spatial long-term, delayed recall Hippocampus 74.4 0.219 0.003 MB atrophy -9.7 0.446 <0.001** Entorhinal white matter 193.3 0.119 0.036 Parahippocampal white matter 136.0 0.124 0.033 Precentral white matter -28.0 0.112 0.042 Superior frontal white matter 25.9 0.129 0.029 Isthmus cingulate cortex 82.7 0.110 0.048 Lateral orbitofrontal cortex -32.8 0.126 0.034 Pars orbitalis cortex -72.5 0.109 0.049 Precentral cortex -30.3 0.215 0.004 Frontal cortex -114.5 0.133 0.029 * After correction for multiple comparison, p-values < 0.0025 are statistically significant for the segmentations and p-values of <0.0015 for the parcellations of cortex and white matter. 6