Kim Annink
168 Chapter 7 28 . Kaandorp JJ, Benders MJNL, Derks JB, Bel F van. Fetal hypoxia is an important determinant of birth asphyxia and subsequent adverse outcome: antenatal neuroprotection at term. Paediatrics and Child Health 2010;20:356-61. 29 . Saugstad OD. Role of xanthine oxidase and its inhibitor in hypoxia: reoxygenation injury. Pediatrics. 1996;98:103-7. 30 . Kjellmer I, Andine P, Hagberg H, Thiringer K. Extracellular increase of hypoxanthine and xanthine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia. Brain Res. 1989;478:241-7. 31 . Ono T, Tsuruta R, Fujita M, Aki HS, Kutsuna S, Kawamura Y, et al. Xanthine oxidase is one of the major sources of superoxide anion radicals in blood after reperfusion in rats with forebrain ischemia/reperfusion. Brain Res. 2009;1305:158-67. 32 . Pietz J. GN, Gluck L. Hypoxanthine: a marker for asphyxia. Obstet Gyneacol 1988;72:762-6. 33 . Beckman JS. The double-edged role of nitric oxide in brain function and superoxide- mediated injury. J Dev Physiol. 1991;15:53-9. 34 . van den Tweel ER, Nijboer C, Kavelaars A, Heijnen CJ, Groenendaal F, van Bel F. Expression of nitric oxide synthase isoforms and nitrotyrosine formation after hypoxia-ischemia in the neonatal rat brain. J Neuroimmunol. 2005;167:64-71. 35 . Hedtjarn M, Mallard C, Hagberg H. Inflammatory gene profiling in the developing mouse brain after hypoxia-ischemia. J Cereb Blood Flow Metab. 2004;24:1333-51. 36 . Scheepens A, Wassink G, Blanco CE. The effect of a global birth asphyxia on the ontogeny of BDNF and NGF protein expression in the juvenile brain. Brain Res. 2003;140:215-21. 37 . Skoff RP, Bessert D, Barks JD, Silverstein FS. Plasticity of neurons and glia following neonatal hypoxic-ischemic brain injury in rats. Neurochem Res. 2007;32:331-42. 38 . Williams GD, Palmer C, Heitjan DF, Smith MB. Allopurinol preserves cerebral energy metabolism during perinatal hypoxia-ischemia: a 31P NMR study in unanesthetized immature rats. Neurosci Lett. 1992;144:103-6. 39 . Palmer C, Vannucci RC, Towfighi J. Reduction of perinatal hypoxic-ischemic brain damage with allopurinol. Pediatr Res. 1990;27:332-6. 40 . Palmer C, Towfighi J, Roberts RL, Heitjan DF. Allopurinol administered after inducing hypoxia-ischemia reduces brain injury in 7-day-old rats. Pediatr Res. 1993;33:405-11. 41 . Peeters-Scholte C, van den Tweel E, Ioroi T, Post I, Braun K, Veldhuis W, et al. Pharmacological interventions in the newborn piglet in the first 24 h after hypoxia- ischemia. A hemodynamic and electrophysiological perspective. Exp Brain Res. 2002;147:200-8.
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