Kim Annink

20 Chapter 1 challenges (67). Even though 7.0T MRI is safe in adults (68), we should first investigate the safety and feasibility of 7.0T MRI in infants in a pilot study. Before starting such a study, we should be able to reliably measure brain temperature during MRI to evaluate the safety. MRS can be used to measure brain temperature in neonates (69,70), but the feasibility of this method without calibration and using different scan protocols is not yet elucidated. In chapter ten, the feasibility of measuring brain temperature with MRS in infants with HIE is assessed. In chapter eleven, the safety preparations and feasibility of 7.0T MRI in infants are discussed.