Kim Annink

22 Chapter 1 REFERENCES 1 . Azzopardi D, Strohm B, Marlow N, Brocklehurst P, Deierl A, Eddama O, et al. Effects of Hypothermia for Perinatal Asphyxia on Childhood Outcomes. N Engl J Med. 2014;371(2):140–9. 2 . Lee ACC, Kozuki N, Blencowe H, Vos T, Bahalim A, Darmstadt GL, et al. Intrapartum- related neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990. Pediatr Res. 2013;74:50–72. 3 . Herrera CA, Silver RM. Perinatal Asphyxia from the Obstetric Standpoint: Diagnosis and Interventions. Clin Perinatol. 2016;43(3):423–38. 4 . Martin-Ancel A, Garcia-Alix A, Cabanas F, Burgueros M, Quero J. Multiple organ involvement in perinatal asphyxia. J Pediatr. 1995;127(5):786–93. 5 . van Bel F, Groenendaal F. Drugs for neuroprotection after birth asphyxia: Pharmacologic adjuncts to hypothermia. Seminars in Perinatology. 2016;40:152-159. 6 . Ferriero DM. Neonatal Brain Injury. N Engl J Med. 2004;351(19):1985–95. 7 . Hilton GD, Nunez JL, Bambrick L, Thompson SM, McCarthy MM. Glutamate- mediated excitotoxicity in neonatal hippocampal neurons is mediated by mGluR- induced release of Ca++ from intracellular stores and is prevented by estradiol. Eur J Neurosci. 2006;24:3008-3016. 8 . Saugstad OD. Role of Xanthine Oxidase and Its Inhibitor in Hypoxia: Reoxygenation Injury. Pediatrics. 1996;98:103-107. 9 . Saugstad OD, Oei JL, Lakshminrusimha S, Vento M. Oxygen therapy of the newborn from molecular understanding to clinical practice. Pediatr Res 2019;85(1):20–9. 10 . Qin X, Cheng J, Zhong Y, Mahgoub OK, Akter F, Fan Y, et al. Mechanism and treatment related to oxidative stress in neonatal hypoxic-ischemic encephalopathy. Front Mol Neurosci. 2019;12:1–10. 11 . Dirnagl U, Lindauer U, Them A, Schreiber S, Pfister HW, Koedel U, et al. Global cerebral ischemia in the rat: Online monitoring of oxygen free radical production using chemiluminescence in vivo. J Cereb Blood Flow Metab. 1995;15(6):929–40. 12 . Ono T, Tsuruta R, Fujita M, Aki HS, Kutsuna S, Kawamura Y, et al. Xanthine oxidase is one of the major sources of superoxide anion radicals in blood after reperfusion in rats with forebrain ischemia/reperfusion. Brain Res. 2009;1305:158-167. 13 . Nijboer CH, Heijnen CJ, Groenendaal F, May MJ, Van Bel F, Kavelaars A. A dual role of the nf-kappa b pathway in neonatal hypoxic-ischemic brain damage. Stroke. 2008;39(9):2578–86.