Kim Annink

61 Cerebellar injury in HIE: MRI versus histopathology Figure 4: Comparisons between ADC values and histopathology in infants with HIE. The per- centage of normal PCs/neurons is presented at the left y-axis and the number of normal PCs/ neurons at the right y-axis. A. ADC values in the vermis were significantly correlated with the count of normal PCs per 1000µm (r=0.59, p<0.01) and the percentage of normal PCs (r=0.50, p=0.01) in the vermis. B. ADC values in the vermis were not different among the CD68 catego- ries (p=0.39) or the HLA-DR categories (p=0.89). C. ADC values in the cerebellar hemispheres were not correlated with the count of normal PCs per 1000µm (r=0.14, p=0.46) nor with the percentage of normal PCs (r=0.0, p≈1.00) in the hemispheres. D. The ADC values in the cere- bellar hemispheres were not different among the CD68 categories (p=0.59) and the HLA-DR categories (p=0.64) in the hemispheres. E. ADC values in the DN were not correlated with the count of normal neurons per 1000µm in the DN (r=0.29, p=0.11) nor with the percentage of normal neurons (r=0.25, p=0.17). F. The ADC values in the DN were comparable between the different CD68 categories (p=0.46) and the HLA-DR categories (p=0.26) in the DN. 3

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