Kim Annink

79 Cerebral ultrasound scoring system for neonates with HIE Baseline characteristics were comparable between the two cohorts except for Apgar scores (Table 2). The mean Apgar scores were lower in Cohort II. Four infants had a postnatal collapse within two hours after birth, which explains their high Apgar scores. The reason for incomplete hypothermia in all infants was early rewarming because of redirection of care. The reason of death in both cohorts was redirection of care based on a poor neurological prognosis. Table 2: Baseline characteristics. Patient characteristic Cohort I (n=83) Cohort II (n=35) p-value Male, n (%) 50 (60.2) 19 (54.3) 0.55 Gestational age, median weeks +days (range) 40 +1 (36 +0 –42 +4 ) 39 +6 (36 +3 –41 +6 ) 0.18 Birth weight, median in gram (range) 3500 (2260-5000) 3425 (1780-4440) 0.36 Mode of delivery Emergency caesarian section, n (%) Vaginal delivery, n (%) Vacuum extraction, n (%) 46 (55.4) 25 (30.1) 12 (14.5) 20 (57.1) 6 (17.1) 9 (25.7) 0.07 Apgar score at 5 minutes, median (range) 3 (0-10) 3 (0-9) <0.001 First pH, median (range) 6.96 (6.53-7.34) 6.94 (6.60-7.28) 0.67 Thompson score, median (range) 10 (4-19) 11 (5-20) 0.83 Sarnat classification Mild, n (%) Moderate, n (%) Severe, n (%) 5 (6.0) 58 (69.9) 20 (24.1) 5 (14.3) 19 (54.3) 10 (28.6) 0.87 Incomplete hypothermia<72 hours, n (%) 6 (7.2) 0 (0) 0.10 Post menstrual age at CUS day 3-7, median days (range) 4 (3-7) 4 (3-7) 0.49 MRI available, n (%) 77 (92.8) N/A N/A Postmenstrual age at MRI, median days (range) 6 (3-16) N/A N/A Outcome Normal, n (%) Adverse outcome < 85, on BSITD-III, n (%) Death, n (%) 54 (65.1) 3 (3.6) 26 (31.3) 17 (48.6) 7 (20.0) 11 (31.4) 0.26 4