Kim Annink

88 Chapter 4 system provides a tool for prospective clinical trials. Probably, the predictive value of the CUS scoring system will further improve when researchers and clinicians will focus even more on the quality using standard scan protocols in prospective studies. CONCLUSIONS In summary, this novel CUS scoring system provides a tool to structurally assess brain injury and predict outcome in HIE if MRI is not feasible or available. It is an easy tool to use in clinical practice and is the first validated CUS scoring system in HIE. In the future, this CUS scoring system should be tested prospectively in infants with HIE. ACKNOWLEDGMENTS The authors thank all neonatologists, fellows and physician assistants from the University Medical Center Utrecht and the Erasmus Medical Center for conducting the cerebral ultrasounds, and Robbin de Goederen, PhD student in the Erasmus Medical Center, for his help with collecting the cerebral ultrasounds for the validation cohort. Members of eurUS.brain are listed in the Editorial for this supplement. The members have read and approved this issue. The authors thank the European Society for Paediatric Research (ESPR) for the opportunity to present their work on the ESPR meeting in 2017 and the Pediatric Academic Society (PAS) to present a poster on the PAS meeting in 2017. FUNDING Funding for this publication was provided by the European Society for Paediatric Research (ESPR). The PhD position of the first author Kim V. Annink is funded by the Horizon 2020 research and innovation Program of the European Union (call H2020- PHC-2015-two-stage, grant 667224, ALBINO). DISCLOSURES Dr. Groenendaal is the founder of 2-iminobiotin and medicolegal expert in cases of perinatal asphyxia. FG also received grant support from Neurophyxia (www. neurophyxia.com ) and is an expert witness in legal cases. LdV received royalties for two books, one on cranial ultrasound and the other on aEEG. CR received a lecture fee from Chiesi Pharmacuticals. The other authors have no conflict of interest to declare.