Caren van Roekel

100 Chapter 3 known to be in a debilitating physical condition, which likely influences their QoL. There were no other variables that had a significant influence on QoL. FIGURE 3. Global health status in patients with different WHO performance scores. The black lines depict the development of GHS per patient. The blue lines with shaded area represent the geometric mean with standard deviation. BL = baseline, 1w = 1 week, 6w = 6 weeks, 3m = 3 months, 6m = 6 months, 9m = 9 months, 12m = 12 months. The GHS score was used as a general measure of QoL and is based on 2 questions. The other 49 questions (i.e. functioning and symptom scores) provide further insights why GHS changed. In this study, role functioning and