Caren van Roekel

292 Chapter 11 This thesis describes the application of holmium-166 ( 166 Ho) radioembolization for patients with hepatic metastases of colorectal carcinoma (mCRC patients). The chapters describe different treatment-related aspects that can be used for individualized treatment. Chapter 3 describes the quality of life, which is especially important in elderly people in a salvage setting. Chapter 4 describes the benefits and drawbacks of a one-day treatment strategy, that could be beneficial for selected patients. Chapter 5 describes the types of response and the influence of several baseline characteristics on response. This could be used for patient selection. Chapters 6 and 7 describe the dose-response relation, which is of vital importance in individualized treatment planning and activity calculation. Chapters 8 and 9, finally, describe the effect of procedure- related interventions: the use of coil-embolization and the use of an anti-reflux catheter.