Caren van Roekel

97 Quality of life in patients treated with 166 Ho-radioembolization Compliance Fifty of 53 patients (94%) filled out the baseline questionnaire and at least 1 follow-up questionnaire. Since patients were withdrawn from the HEPAR II study after diagnosis of progressive disease, there was quite some variability in follow-up time. Three patients failed to fill out the questionnaire at baseline and 3 months after treatment and were therefore excluded from analysis. Three patients failed to fill out a follow-up questionnaire (1 patient at 6 weeks and 2 patients at 6 months after treatment) and these questionnaires were pairwise excluded from analysis. Four patients left a question blank. Development of QoL Median and interquartile ranges of all categories at the different time points are listed in table S3 and graphically displayed in Figures 1 and 2 and supplemental figure S3a-d. Cronbach’s alpha was determined for the multi-item scales at baseline and at 3 months follow-up and varied from 0.52-0.95 (Table S2). FIGURE 1. Median global health score over time with interquartile range (shaded area). A high score represents a good health score. 3

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