Caren van Roekel

99 Quality of life in patients treated with 166 Ho-radioembolization FIGURE 2. Median role functioning scores over time with interquartile ranges (shaded areas). BL = baseline, 1w = 1 week, 6w = 6 weeks, 3m = 3 months, 6m = 6 months, 9m = 9 months, 12m = 12 months. A high score represents good functioning. DISCUSSION The purpose of the current study was to evaluate the effect of 166 Ho-RE on QoL, which has never been studied before. The hypotheses were that there would be no significant change in QoL over time and that the post-embolization syndrome would have an impact on QoL. This study showed that the first hypothesis was correct: QoL was not significantly affected over time, although there was a lot of variation between and within patients. Regarding the second hypothesis; a decline in QoL and a rise of symptoms was seen at one week post-treatment, which is most likely due to the post-embolization syndrome, however, this was not statistically significantly different from the scores at baseline. In the linear mixed model analysis, it was shown that a higher WHO performance score significantly influenced PF, RF, SF, FA, DY, DI and LMCFati. This is not surprising, as patients with a higher WHO performance score are 3