Koos Boeve

111 Cyclin D1 in early oral cancer Figure 2. Fluorescence in-situ hybridization of CCND1 in oral cancer. Signals: DAPI, nucleus; green, centromere chromosome 11; red, CCND1 gene. A. normal copy number. B. polysomy chromosome 11. C. low-level amplification. D. high-level amplification.