Koos Boeve

137 Molecular biomarkers in SLNB staged early oral cancer SUPPLEMENTARY DATA Supplementary data 1. Number of cores per tumor for each marker and corresponding intraclass correlation coefficient Cortactin Cyclin D1 FADD RAB25 S100A9 nucleus S100A9 cyto † 1 core 4 8 9 4 5 5 2 cores 22 22 18 26 27 27 3 cores 56 52 54 52 50 50 ICC 0.71 0.70 0.86 0.66 † 0.72 0.81 (95% CI) (0.58 to 0.81) (0.57 to 0.80) (0.79 to 0.91) (0.53 to 0.77) (0.53 to 0.85) (0.72 to 0.93) ICC is based on cases with 3 cores. † ICC based on the average percentage of any (moderate and strong) staining per core ICC: <0“poor,”0 to 0.20“slight,”0.21 to 0.4“fair,”0.41 to 0.60“moderate”, 0.61 to 0.80“substantial”, >0.81“almost perfect” Abbreviations: ICC, intraclass correlation coefficient; cyto, cytoplasmic; CI, confidence interval.