Koos Boeve

CHAPTER 8 Detection of tumor cells in saliva from patients with oral squamous cell carcinoma using DNA hypermethylation of KCNA5 and TIMP3 K. Boeve 1,2 *, M.J.A.M. Clausen 1,2 *, L.J. Melchers 1,2 *, L. Slagter-Menkema 2,3 , M.F. Mastik 2 , G.B.A. Wisman 4 , B. van der Vegt 2 , T. de Meyer 5,6 , W. van Criekinge 5 , M.J.H. Witjes 1 , J.L.N. Roodenburg 1 **, E. Schuuring 2 ** * Authors contributed equally to this work, ** Both authors contributed equally to this work. Manuscript submitted Departments of Oral and Maxillofacial Surgery 1 , Pathology & Medical Biology 2 , Otorhinolaryngology / Head & Neck Surgery 3 , Gynaecologic Oncology 4 , University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Department of Data Analysis and Mathematical Modelling 5 , Ghent University, Ghent, Belgium. MRB 6 , Cancer Research Institute Ghent, Ghent, Belgium.