Koos Boeve

161 Methylation biomarkers for the detection of tumor DNA in saliva Supplementary data 1. Continued Gene name Chromosome locus Gene regio start (GSE42409) Gene regio end (GSE42409) p-value (Mann- Whitney U test) Number of reads OSCC patient 1 OSCC patient 2 OSCC patient 3 OSCC patient 4 OSCC patient 5 OSCC patient 6 OSCC patient 7 OSCC patient 8 OSCC patient 9 OSCC patient 10 OSCC patient 11 OSCC patient 12 Leukocyte pool 1 Leukocyte pool 2 C21orf77 21 33948372 33948737 0.002 7 11 6 8 5 9 13 9 4 6 10 10 12 13 ACAP3 1 1246319 1246922 0.002 6 18 10 8 15 9 16 17 14 11 15 8 17 17 ADAD2 16 84224448 84224795 0.002 6 11 10 11 5 5 12 16 10 5 15 9 14 14 KIAA0323 14 24897965 24898530 0.002 4 8 5 9 4 6 6 13 7 7 9 7 10 10 C2CD2 21 43374507 43375097 0.002 4 14 10 9 11 7 10 16 16 8 14 3 15 16 TIMM13 19 2428888 2429827 0.002 10 10 12 10 6 4 16 15 9 9 12 8 14 14 AC110299.1 2 242456556 242457232 0.002 4 8 8 8 7 8 8 9 11 5 9 6 12 13 U1 1 146550207 146550837 0.002 7 18 7 4 4 9 22 15 8 5 8 5 2 3 AP005380.2 18 5132955 5133396 0.002 3 11 6 9 7 3 11 12 10 6 13 4 12 13 SETDB1 1 150896594 150896961 0.002 8 6 3 9 6 4 12 10 8 4 8 4 10 10 AC103563.10 2 95638175 95638602 0.002 3 9 8 6 6 4 6 10 6 9 12 6 10 10 CALM2 2 47405104 47405186 0.002 0 1 1 0 1 0 0 1 0 1 1 1 0 0 MSMB 10 51548149 51548150 0.002 1 0 1 0 1 0 1 0 1 1 1 0 0 0 GLS2 12 56881692 56881936 0.002 0 0 1 0 1 1 1 1 1 0 1 0 0 0 HSD11B2 16 67463366 67463367 0.002 0 0 1 1 1 0 1 0 1 0 1 1 0 0 ETV2 19 36132506 36132707 0.002 0 1 0 1 1 0 1 1 0 1 1 0 0 0 FCRLB 1 161689631 161689644 0.002 0 1 1 1 0 0 1 1 0 1 1 0 0 0 LIPA 10 91175701 91176201 0.002 3 10 7 5 4 8 10 10 7 7 10 5 10 10 SYT14 1 210111479 210111996 0.003 9 4 3 3 4 12 16 12 8 5 4 2 2 1 SKI 1 2157600 2158529 0.003 8 8 4 7 7 8 6 13 6 5 9 7 12 11 ELF5 11 34534937 34535481 0.003 7 13 7 6 4 7 7 15 4 7 16 9 13 13 AC133919.5 16 90160195 90160692 0.003 6 14 8 6 8 6 10 11 11 4 7 7 5 5 AC012075.1 2 81694490 81694825 0.003 5 13 6 9 4 8 8 17 8 6 14 3 14 13 SFRS6 20 42084031 42084724 0.003 7 8 3 5 8 7 5 10 6 9 8 6 9 9 AC006269.1 17 53638377 53639063 0.003 6 16 10 6 7 7 17 15 14 8 13 7 15 16 AC018804.7 2 130986044 130986416 0.003 10 9 7 7 6 4 13 16 10 10 12 5 13 14 AC025279.1 16 29300194 29301153 0.003 5 9 6 8 9 9 4 9 12 12 12 7 13 12 hsa-mir-410 14 101532662 101533132 0.003 3 11 5 12 7 7 5 13 13 6 10 5 12 13 WDR24 16 738987 739624 0.003 19 15 12 14 8 8 15 15 18 8 19 10 18 18 LRRC30 18 7231085 7231660 0.003 6 19 5 10 4 6 13 13 12 8 11 4 15 14 C16orf81 16 89225822 89226056 0.003 5 13 5 10 8 9 7 12 9 3 12 8 12 13 C17orf62 17 80409641 80409982 0.003 7 9 7 4 7 6 9 9 6 7 10 4 5 5 AC080112.1 17 38523323 38523956 0.003 6 9 6 8 7 4 5 13 7 7 10 7 10 10 F2 11 46741219 46741868 0.003 9 15 7 8 8 12 7 15 8 7 11 7 14 13 AL359457.2 13 20134785 20135212 0.003 5 12 8 6 5 6 6 16 10 8 11 7 13 12 AP001266.1 11 65546062 65546392 0.003 9 13 10 9 6 8 13 12 16 12 14 9 14 14 AL356961.2 13 112760878 112761112 0.003 8 4 8 4 1 9 17 11 7 1 9 2 2 1 SYT8 11 1846938 1847982 0.004 8 18 12 17 10 14 10 28 6 9 21 11 20 21 GPR25 1 200842396 200842812 0.004 7 7 8 7 9 14 19 10 7 2 11 10 5 4 C2orf65 2 74875016 74875561 0.004 7 9 6 6 8 8 7 12 7 4 12 5 5 5 CASP7 10 115478883 115479141 0.004 6 9 6 7 7 6 15 8 12 8 9 6 4 5