Koos Boeve

165 Methylation biomarkers for the detection of tumor DNA in saliva Supplementary data 1. Continued Gene name Chromosome locus Gene regio start (GSE42409) Gene regio end (GSE42409) p-value (Mann- Whitney U test) Number of reads OSCC patient 1 OSCC patient 2 OSCC patient 3 OSCC patient 4 OSCC patient 5 OSCC patient 6 OSCC patient 7 OSCC patient 8 OSCC patient 9 OSCC patient 10 OSCC patient 11 OSCC patient 12 Leukocyte pool 1 Leukocyte pool 2 JMJD4 1 227921399 227921906 0.019 3 6 6 7 7 14 13 9 12 5 12 6 11 12 GALNT13 2 154728002 154728308 0.020 9 1 3 1 3 4 14 7 0 4 2 2 1 1 RNF17 13 25337805 25338421 0.020 5 9 10 7 4 6 8 16 8 5 14 8 12 11 AC112777.1 12 20704358 20704532 0.020 9 14 9 21 5 10 8 13 13 6 33 5 19 18 C21orf33 21 45551474 45551798 0.020 3 10 4 14 6 5 10 14 8 4 13 6 12 11 GP1BA 17 4836017 4836468 0.021 8 9 3 9 7 5 16 11 6 8 13 5 12 11 AL592464.2 1 2729504 2730299 0.021 8 17 8 11 8 8 20 18 13 9 14 4 16 15 SNX32 11 65601265 65601550 0.021 0 2 0 3 2 14 0 13 3 2 7 0 0 0 KAT2A 17 40274881 40275820 0.021 9 10 11 12 7 9 11 14 7 6 14 6 15 17 NNAT 20 36149825 36150208 0.021 7 12 7 7 3 11 11 20 10 8 8 5 5 6 KIAA0562 1 3774998 3775624 0.021 6 15 3 8 12 8 5 12 5 9 16 10 13 12 AL117692.1 14 50519321 50519571 0.021 6 9 5 5 9 3 7 12 7 5 10 4 10 9 AL109945.1 1 32815223 32815649 0.022 8 7 6 5 11 10 10 10 9 8 8 5 6 5 hsa-mir-380 14 101491469 101492406 0.022 5 15 7 8 9 12 10 15 13 7 16 6 13 14 GRK1 13 114321368 114322096 0.022 6 15 9 8 5 8 10 19 12 8 12 7 13 13 TCL1A 14 96179944 96180575 0.022 10 6 8 5 5 11 9 17 7 8 8 7 13 15 snoU13 17 77685085 77685964 0.022 3 11 4 8 4 10 7 10 9 5 15 6 12 14 AMN 14 103388267 103388745 0.023 5 12 5 5 6 9 3 14 8 7 11 6 10 11 DSCR4 21 39493391 39493628 0.023 6 12 4 8 9 7 12 15 8 9 6 8 11 11 ASPA 17 3375365 3375814 0.023 8 8 6 6 6 8 15 11 7 8 12 4 13 15 NTN5 19 49176094 49176747 0.023 10 8 12 7 12 8 16 17 8 8 16 8 17 15 NAV1 1 201591881 201592262 0.024 10 20 5 11 7 14 18 10 8 4 16 5 6 7 AC004448.7 17 19396521 19397115 0.024 4 7 8 8 6 5 8 5 6 7 10 7 8 8 NEFH 22 29876170 29876886 0.024 9 12 11 8 7 12 21 16 11 5 10 9 8 7 AL158216.1 1 42506718 42507155 0.025 9 10 4 5 6 10 15 8 8 6 8 4 10 11 PAOX 10 135193152 135194112 0.025 3 8 15 18 10 9 10 19 11 6 10 4 14 14 AC068134.5 2 233252919 233253570 0.025 5 13 8 6 9 8 14 14 8 8 13 2 13 15 MBD3 19 1593742 1594594 0.025 7 7 7 10 7 3 16 12 6 5 14 6 11 12 AP002347.1 11 59665177 59665838 0.025 10 14 10 8 5 7 16 10 8 11 9 10 13 12 P4HA3 11 74021586 74022694 0.026 4 5 9 7 7 9 11 8 10 6 15 9 13 15 ACTRT2 1 2936088 2936661 0.026 5 12 5 5 5 11 12 10 8 3 10 6 12 14 EP400NL 12 132567723 132568038 0.026 5 7 7 10 4 3 11 8 5 8 11 5 5 5 SFT2D3 2 128456522 128456875 0.026 7 20 10 6 11 8 8 15 10 7 19 9 14 15 PROKR2 20 5294594 5294876 0.027 5 19 6 9 9 14 13 15 14 7 12 7 14 14 AC018731.1 2 152042525 152042811 0.028 5 11 10 7 4 7 14 6 8 9 8 7 6 6 AC105272.1 1 104112490 104113282 0.028 8 9 5 5 11 10 9 16 8 5 9 10 11 11 AL034420.1 20 50481186 50481798 0.028 6 12 9 6 8 4 12 10 9 9 8 4 13 15 WDR90 16 697261 697875 0.028 9 11 6 8 5 15 4 11 14 8 12 6 15 13 FAM83E 19 49116077 49116544 0.029 4 17 8 7 6 3 7 16 4 8 7 7 11 11 AP001187.6 11 64658499 64658834 0.029 5 16 9 8 7 9 5 15 10 12 8 10 12 12 PROX1 1 214156052 214156507 0.029 5 2 5 6 4 13 20 10 1 3 11 4 3 1