Koos Boeve

48 Chapter 2 SUPPLEMENTARY DATA Supplementary data 1. Disease specific survival rates , 95% confidence intervals and log-rank test of all stages after excluding watchful waiting patients with a tumour infiltration depth > 4 mm Edition Category Disease Specific Survival Log-Rank test 5 yr % 95% CI Compared stages p-value 7 th pT T1 92 85 to 96 T1 vs T2 0.001 T2 72 61 to 81 8 th pT T1 92 83 to 97 T1 vs T2 0.066 T2 82 73 to 89 T2 vs T3 0.042 T3 66 45 to 80 T1 vs T3 0.001 7 th pN WW 100 NA WW vs N0 0.135 N0 92 84 to 96 N0 vs N1 0.005 N1 73 54 to 86 N1 vs N2 0.264 N2 59 42 to 73 N2 vs N3 0.402 N3 0 NA NA 8 th pN WW 100 NA WW vs N0 0.135 N0 92 84 to 96 N0 vs N1 0.016 N1 75 53 to 88 N1 vs N2 0.793 N2 69 46 to 84 N2 vs N3 0.072 N3 48 26 to 67 7 th SG WW 100 NA WW vs Stage I 0.333 Stage I 96 86 to 99 Stage I vs Stage II 0.056 Stage II 85 70 to 93 Stage II vs Stage III 0.184 Stage III 73 54 to 86 Stage III vs Stage IV 0.220 Stage IV 58 40 to 72 8 th SG WW 100 NA WW vs Stage I 0.352 Stage I 97 79 to 100 Stage I vs Stage II 0.594 Stage II 94 83 to 98 Stage II vs Stage III 0.007 Stage III 74 58 to 85 Stage III vs Stage IV 0.167 Stage IV 59 43 to 72 Abbreviations: CI, confidence interval; N, nodal; T, tumor; NA, not applicable; SG, stage grouping; WW, watchful waiting