Koos Boeve

01 General introduction and scope of this thesis 9 02 Addition of tumor infiltration depth and extranodal extension improves the prognostic value of the pathological TNM classification for early stage oral squamous cell carcinoma 35 03 High sensitivity and negative predictive value of sentinel lymph node biopsy in a retrospective early stage oral cavity cancer cohort in the Northern Netherlands 53 04 High rate of unexpected lymphatic drainage patterns and a high accuracy of the sentinel lymph node biopsy in oral cancer after previous neck treatment 71 05 Lymphatic drainage patterns of oral maxillary tumors: Approachable locations of sentinel lymph nodes mainly at the cervical neck level 87 06 Amplification and protein overexpression of cyclin D1: Predictor of occult nodal metastasis in early oral cancer 101 CONTENTS