Koos Boeve

92 Chapter 5 non-sentinel lymph nodes were investigated by routine histopathological examination (standardH&E staining, without step-serial-sectioning or additional immunohistochemistry), or in some cases using step-serial-sectioning and both stainings. The sentinel lymph node slides were revised by a dedicated head & neck pathologist (B.v.d.V.). Table 2. Sentinel lymph node biopsy information Patient # SLNB side Ipsilateral neck surgery Parapharyngeal SLN* No. of harvested SLNs † No. of harvested non-SLNs 1 Ipsilateral SLNB None 3 1 2 Ipsilateral SLNB Yes, ipsilateral 1 0 3 Contralateral None ‡ None 2 2 4 Contralateral END None 1 0 5 Contralateral END None 1 0 6 Contralateral END None 1 1 7 Contralateral MRND Yes, contralateral 4 2 8 Contralateral MRND None 1 0 9 Bilateral SLNB None 2 1 10 Bilateral SLNB None 3 0 11 § NA NA None 0 0 Abbreviations: SLNB; sentinel lymph node biopsy, END; elective neck dissection, MRND; modified radical neck dissection, SLN; sentinel lymph node, No.; number. * Parapharyngeal SLN detected with lymphoscintigraphy. † Number of harvested lymph nodes marked as SLNs ‡ Ipsilateral treated by END and radiotherapy in the past § Patient #11 had no detectable SLNs at the lymphoscintigraphy RESULTS Patients In total, 11 patients with oral maxillary cancer were analyzed: 10 patients with primary maxillary OSCC and 1 patient with a primary maxillary mucosal melanoma (Table 1), 3 men and 8 women aged between 54 and 90 years at the time of treatment. Two patients had previous OSCC treated by resection, neck dissection and postoperative radiotherapy at the same side (patient #3) and the other side (patient #9) as the maxillary OSCC tumor. Patient #11 had previous treatment with neck dissection and radiotherapy because of a pN3 OSCC metastasis by unknown primary.