Koos Boeve

01 General introduction and scope of this thesis	9
02 Addition of tumor infiltration depth and extranodal extension improves the prognostic value of the pathological TNM classification for early stage oral squamous cell carcinoma	35
03 High sensitivity and negative predictive value of sentinel lymph node biopsy in a retrospective early stage oral cavity cancer cohort in the Northern Netherlands	53
04 High rate of unexpected lymphatic drainage patterns and a high accuracy of the sentinel lymph node biopsy in oral cancer after previous neck treatment	71
05 Lymphatic drainage patterns of oral maxillary tumors: Approachable locations of sentinel lymph nodes mainly at the cervical neck level	87
06 Amplification and protein overexpression of cyclin D1: Predictor of occult nodal metastasis in early oral cancer	101
07 In T1N0 staged oral squamous cell carcinomas with a tumor infiltration depth below 4 mm cortactin expression is associated with lymph node status	123
08 Detection of tumor cells in saliva from patients with oral squamous cell carcinoma using DNA hypermethylation of KCNA5 and TIMP3	143
09 General discussion and future perspectives	175
10 English summary & Nederlandse samenvatting	201
List of publications	215
Dankwoord	217
Curriculum vitae	223

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