Xuxi Zhang

HDL: 50±14 BMI: 21.7±1.8 Without diabetic retinopathy (%): 100 LDL:  ‐  HDL: 53±14 BMI: 21.2±2.3 Without diabetic retinopathy (%): 100 Secondary ‐ intervention cohort (patients with simple retinopathy) Baseline and follow ‐ up (6 years) † :IG:26 CG: 25 Patients with type 2 diabetes Female (%): 53.9 Mean age: 49±13 Duration of diabetes (year): 10.2±4.2 HbA1c (%): 9.4±1.8 Blood pressure (mm Hg): Systolic: 121±11 Diastolic: 70±8 Total Cholesterol (mg/dl): LDL:  ‐  HDL: 52±19 BMI: 19.3±1.7 Without diabetic retinopathy (%): 0 Patients with non ‐ insulin ‐ dependent diabetes Female (%): 56 Mean age: 52±15 Duration of diabetes (year): 10.3±4.9 HbA1c (%): 9.0±1.9 Blood pressure (mm Hg): Systolic: 123±9 Diastolic: 70±7 Total Cholesterol (mg/dl): LDL:  ‐  HDL: 55±23 BMI: 19.2±2.8 Without diabetic retinopathy (%): 0 RCT Japan Glycemic ‐ control intervention Multiple insulin injection treatment vs. Conventional insulin injection treatment Tovi, 1998 Baseline and Follow ‐ up (1 year) ‡ IG: 19 CG: 16 Patients with type 2 diabetes Female (%): 57.9 Mean age: 73±5 Duration of diabetes (year): 12±7 HbA1c (%): 9.3±1.4 Blood pressure (mm Hg): Systolic: 155±17 Diastolic: 78±10 Total Cholesterol (mg/dl): LDL:  ‐  HDL:  ‐  BMI: 26.3±4.6 Without diabetic retinopathy (%): 26.3 Patients with type 2 diabetes Female (%): 56.3 Mean age: 77±6 Duration of diabetes (year): 11±7 HbA1c (%): 9.1±1.1 Blood pressure (mm Hg): Systolic: 158±17 Diastolic: 80±9 Total Cholesterol (mg/dl): LDL:  ‐  HDL:  ‐  BMI: 28.3±4.3 Without diabetic retinopathy (%): 56.2 RCT Sweden Glycemic ‐ control intervention Insulin treatment vs. sulphonylurea treatment 182 Chapter 7

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