Xuxi Zhang

Supplementary Table S4 Risk of Bias Study Selection bias Performance bias Detection bias Attrition bias Reporting bias Other bias ABCD trail, 2002 Low risk Unclear risk Unclear risk Low risk Low risk Low risk ACCORD Eye Study, 2010 Low risk Unclear risk Unclear risk Low risk Low risk Low risk ACCORDION Eye Study, 2016 Low risk Unclear risk Unclear risk Low risk Low risk Low risk Kumamoto, 1995 Unclear risk High risk Unclear risk Low risk Low risk Low risk Tovi, 1998 Unclear risk High risk Unclear risk Low risk Unclear risk Low risk Steno study, 1999 Unclear risk High risk Unclear risk Low risk Unclear risk Low risk Steno 2 study, 2003 Unclear risk High risk Unclear risk Low risk Unclear risk Low risk Rachmani, R., 2002 Low risk High risk Unclear risk Low risk Unclear risk Low risk PREDIMED study, 2015 Low risk Unclear risk Unclear risk Low risk Unclear risk Low risk UKPDS 69, 2004 Unclear risk Unclear risk Unclear risk Low risk Low risk Low risk VADT, 2016 Low risk Unclear risk Unclear risk Low risk Low risk Low risk ADVANCE, 2008 Unclear risk Unclear risk Unclear risk Low risk Low risk Low risk AdRem Study, 2009 Unclear risk Unclear risk Unclear risk Low risk Low risk Low risk California Medi ‐ Cal Study, 2005 Unclear risk Unclear risk Unclear risk Unclear risk Low risk Low risk Lifestyle intervention, 2002 Unclear risk Unclear risk Low risk Unclear risk Unclear risk Low risk VA CSDM, 1996 Unclear risk High risk Unclear risk Low risk Low risk Low risk 194 Chapter 7