Xuxi Zhang

Supplementary Table S4 Multivariate linear regression model (Score of three domains of frailty and HRQoL) Items PCS MCS Crude Model Adjusted Model Crude Model Adjusted Model Crude Model Adjusted Model Full Model Crude Model Adjusted Model Crude Model Adjusted Model Crude Model Adjusted Model Full Model Frailty (Yes vs. No) Physical frailty ‐ 3.49 c ‐ 2.94 c ‐ 2.99 c ‐ 2.12 c ‐ 1.46 c ‐ 0.47 c Psychological frailty ‐ 2.94 c ‐ 1.78 c 0.30 ‐ 5.58 c ‐ 4.83 c ‐ 4.09 c Social frailty ‐ 2.77 c ‐ 1.56 c ‐ 0.18 ‐ 3.45 c ‐ 4.16 c ‐ 2.26 c Age ‐ 0.10 a ‐ 0.26 c ‐ 0.26 c ‐ 0.10 a 0.13 b 0.07 0.07 0.11 b Sex Female vs. male ‐ 1.26 b ‐ 2.20 c ‐ 2.64 c ‐ 1.31 b ‐ 1.44 b ‐ 0.90 a ‐ 2.10 c ‐ 0.85 a Country The United Kingdom vs. Spain ‐ 5.38 c ‐ 5.03 c ‐ 4.80 c ‐ 5.35 c ‐ 1.61 a ‐ 2.05 b ‐ 1.42 ‐ 2.10 b Greece vs. Spain ‐ 0.14 ‐ 0.50 ‐ 0.98 ‐ 0.23 ‐ 2.41 b ‐ 0.12 ‐ 1.46 0.56 Croatia vs. Spain ‐ 2.44 b ‐ 5.30 c ‐ 5.41 c ‐ 2.42 b ‐ 5.77 c ‐ 5.88 c ‐ 6.21 c ‐ 4.88 c The Netherlands vs. Spain ‐ 5.74 c ‐ 4.84 c ‐ 4.23 c ‐ 5.67 c 0.40 ‐ 0.07 1.57 a 0.17 Education level Primary or less vs. tertiary or higher ‐ 0.71 ‐ 2.07 a ‐ 2.41 b ‐ 0.75 ‐ 2.16 a ‐ 1.48 ‐ 2.42 b ‐ 1.03 Secondary or equivalent vs. tertiary or higher 0.67 0.47 0.25 0.64 ‐ 1.24 ‐ 0.72 ‐ 1.32 ‐ 0.67 Living situation Living alone vs. living with others ‐ 0.08 0.02 1.90 b 0.14 ‐ 0.09 ‐ 0.15 4.88 c 2.50 c Life style Alcohol risk vs. no alcohol risk 0.67 1.78 b 1.95 c 0.68 0.61 0.69 1.16 a 0.50 Exercise once a week or less vs. more than once a week ‐ 5.59 c ‐ 8.90 c ‐ 9.38 c ‐ 5.61 c ‐ 3.55 c ‐ 3.51 c ‐ 4.83 c ‐ 2.77 c 2 47 Association between frailty and HRQoL