Xuxi Zhang

Supplementary Table S4 Multivariate linear regression model (Score of three domains of frailty and HRQoL) (Continued) Items PCS MCS Crude Model Adjusted Model Crude Model Adjusted Model Crude Model Adjusted Model Crude Model Adjusted Model Crude Model Adjusted Model Crude Model Adjusted Model Crude Model Adjusted Model Smoking vs. not smoking 1.20 0.40 0.46 1.22 ‐ 0.33 ‐ 0.85 ‐ 0.69 ‐ 0.70 Multi ‐ morbidity Yes vs. No ‐ 3.75 c ‐ 6.14 c ‐ 6.31 c ‐ 3.74 c ‐ 0.14 ‐ 0.57 ‐ 1.04 ‐ 0.03 Adjusted R 2 , % 38.4 48.0 6.7 30.9 4.1 29.5 48.0 18.0 24.4 30.9 37.9 8.2 24.9 40.4 Note: Abbreviations: PCS, Physical Component Suammary summarized by the SF ‐ 12; MCS, Mental Component Suammary summarized by the SF ‐ 12. The Crude Model is the unadjusted model with one domain of frailty (physical, psychological or social frailty) as determinant. The Adjusted Model is the adjusted model with one domain of frailty (physical, psychological or social frailty) and the covariates as determinants. The Full Model is the adjusted model with physical, psychological and social frailty and the covariates as determinants. a p <0.05, b p <0.01, c p <0.001, significant P ‐ values in bold 48 Chapter 2