Xuxi Zhang

Figure 2 Frailty score at baseline and follow ‐ up of participants from the groups of frequency of moderate physical activity (PA) (A) Baseline PA and overall frailty, (B) Change in PA and overall frailty, (C) Baseline PA and physical frailty, (D) Change in PA and physical frailty, (E) Baseline PA and psychological frailty, (F) Change in PA and psychological frailty, (G) Baseline PA and social frailty, (H) Change in PA and social frailty. 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 BASELINE 12 ‐ MONTH FOLLOW ‐ UP FRAILTY SCORE Baseline Physical Activity(PA) and Overall Frailty Regular frequency of PA at baseline (n=1272) Low frequency of PA at baseline (n=463) 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 BASELINE 12 ‐ MONTH FOLLOW ‐ UP FRAILTY SCORE Change in PA and Overall Frailty Continued regular frequencyofPA (n=1020) Decreased frequencyofPA (n=252) Continued low frequencyofPA (n=302) Increased frequencyofPA (n=161) 0 1 2 3 4 5 6 7 8 BASELINE 12 ‐ MONTH FOLLOW ‐ UP FRAILTY SCORE Baseline PA and Physical Frailty Regular frequency of PA at baseline (n=1272) Low frequency of PA at baseline (n=463) 0 1 2 3 4 5 6 7 8 BASELINE 12 ‐ MONTH FOLLOW ‐ UP FRAILTY SCORE Change in PA and Physical Frailty Continued regular frequencyofPA (n=1020) Decreased frequencyofPA (n=252) Continued low frequencyofPA (n=302) Increased frequencyofPA (n=161) 0 1 2 3 4 BASELINE 12 ‐ MONTH FOLLOW ‐ UP FRAILTY SCORE Baseline PA and Psychological Frailty Regular frequency of PA at baseline (n=1272) Low frequency of PA at baseline (n=463) 0 1 2 3 4 BASELINE 12 ‐ MONTH FOLLOW ‐ UP FRAILTY SCORE Change in PA and Psychological Frailty Continued regular frequencyofPA (n=1020) Decreased frequencyofPA (n=252) Continued low frequencyofPA (n=302) Increased frequencyofPA (n=161) 0 1 2 3 BASELINE 12 ‐ MONTH FOLLOW ‐ UP FRAILTY SCORE Baseline PA and Social Frailty Regular frequency of PA at baseline (n=1272) Low frequency of PA at baseline (n=463) 0 1 2 3 BASELINE 12 ‐ MONTH FOLLOW ‐ UP FRAILTY SCORE Change in PA and Social Frailty Continued regular frequencyofPA (n=1020) Decreased frequencyofPA (n=252) Continued low frequencyofPA (n=302) Increased frequencyofPA (n=161) A B C D E F G H 3 59 Longitudinal association between physical activity and frailty

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