Xuxi Zhang

Table 4 Concurrent validity of the TFI and its three domains (n=2250) Adverse outcomes (measures) Screening Population Cut ‐ off Point * Sensitivity Specificity AUC (95% CI) † Physically frail (SHARE ‐ FI) Full TFI Total ≥ 6 0.80 0.66 0.81(0.79, 0.83) ≥ 7 0.69 0.76 Spain ≥ 6 0.80 0.71 0.84(0.79, 0.89) Greece ≥ 9 0.67 0.90 0.87(0.83, 0.92) Croatia ≥ 8 0.82 0.66 0.81(0.76, 0.85) The Netherlands ≥ 6 0.76 0.78 0.84(0.79, 0.89) The United Kingdom ≥ 5 0.84 0.68 0.84(0.80, 0.87) Physical domain Total ≥ 4 0.77 0.70 0.81(0.79, 0.83) Spain ≥ 4 0.75 0.72 0.82(0.77, 0.87) Greece ≥ 5 0.67 0.82 0.84(0.78, 0.89) Croatia ≥ 6 0.71 0.78 0.80(0.75, 0.84) The Netherlands ≥ 4 0.76 0.83 0.85(0.81, 0.90) The United Kingdom ≥ 3 0.84 0.68 0.83(0.80, 0.87) Loss of independence (GARS) Full TFI Total ≥ 6 0.82 0.69 0.83(0.82, 0.85) Spain ≥ 6 0.89 0.72 0.87(0.83, 0.91) Greece ≥ 8 0.69 0.79 0.81(0.75, 0.87) Croatia ≥ 8 0.74 0.79 0.84(0.81, 0.88) The Netherlands ≥ 5 0.82 0.76 0.86(0.82, 0.90) The United Kingdom ≥ 5 0.84 0.64 0.82(0.78, 0.86) Physical domain Total ≥ 4 0.80 0.74 0.84(0.83, 0.86) Spain ≥ 4 0.89 0.74 0.88(0.83, 0.92) Greece ≥ 5 0.66 0.82 0.83(0.77, 0.88) Croatia ≥ 5 0.79 0.73 0.84(0.81, 0.88) The Netherlands ≥ 4 0.69 0.88 0.85(0.80, 0.89) The United Kingdom ≥ 4 0.70 0.80 0.84(0.80, 0.87) 4 89 Reliability and validity of the TFI