Maarten Cozijnsen

39 Chapter 2 Development and validation of the MINI-index Validation cohort 2 (n=44) Validation cohort 3 (n=38) All validation cohorts (n=168) p-value (derivation vs all validation) 41% 58% 46% 0.411 12.7±5.5 14.6±3.4 14.2±3.9 0.777 0.1 (0-2.8) 0 (0-0) 1.1 (0-2.4) <0.001 3.9±0.5 3.6±0.6 4.1±0.6 0.005 27 (15-44) 35 (26-54) 22 (9-38) 0.952 16.6 (6.3-44) 27.0 (15.5-54.8) 2.5 (0.3-26) 0.021 2100 (555-2100) 835 (622-1130) 620 (68-1067) 0.388 18% 5% 38% 0.187 32% 0% 54% <0.001 30% 3% 12% <0.001 39% 97% 35% 0.002 11 (6-17) 15 (9-21) 6 (0-15) 0.001 9% 3% 36% <0.001 34% 29% 27% 0.107 57% 68% 36% 0.025