Maarten Cozijnsen

49 Chapter 2 Development and validation of the MINI-index Supplementary material Supplementary table 1. Linear regression model for deriving the MINI-index B P-value B P-value B P-value B P-value Constant 4.2 0.00 4.0 0.00 -8.8 0.00 -9.5 0.00 Abdominal pain 5 2.0 0.14 1.9 0.19 1.5 0.23 1.7 0.17 Abdominal pain 10 0.8 0.69 0.7 0.70 1.0 0.57 1.0 0.54 Stool 5 4.2 0.00 4.3 0.00 3.2 0.01 3.0 0.02 Stool 10 9.9 0.00 9.9 0.00 7.7 0.00 7.6 0.00 Weight 5 3.0 0.03 2.6 0.07 2.4 0.05 2.9 0.03 Weight 10 6.4 0.04 6.2 0.04 5.3 0.05 5.5 0.04 Perianal disease 5 3.4 0.15 3.5 0.14 3.3 0.11 3.2 0.12 Perianal disease 10 2.7 0.42 3.0 0.37 3.0 0.31 2.6 0.37 EIM 2.5 -1.3 0.60 -1.3 0.60 -1.1 0.61 -1.1 0.62 HCT 2.5 2.0 0.17 1.9 0.19 0.8 0.53 0.8 0.53 HCT 5 5.3 0.18 5.0 0.21 3.4 0.33 3.7 0.29 Albumin 5 1.9 0.29 1.7 0.35 0.9 0.58 1.1 0.51 Albumin 10 -6.2 0.03 -6.1 0.03 -6.3 0.01 -6.3 0.01 ESR 2.5 1.8 0.16 1.2 0.39 0.2 0.88 0.8 0.51 ESR 5 5.2 0.02 4.1 0.10 3.0 0.13 4.2 0.05 Log CRP 0.4 0.36 -0.6 0.18 Log FC 2.5 0.00 2.7 0.00 Adjusted R 2 0.36 0.36 0.51 0.51 SESCD score served as the dependent variable in all models. All items – except Log CRP and Log FC – are from the PCDAI and scored accordingly. B = unstandardized coefficient; EIM = extraintestinal manifestations; HCT = hematocrit; ESR = erythrocytes sedimentation rate; CRP = C-reactive protein; FC = fecal calprotectin.