Maarten Cozijnsen

89 Chapter 4 Infliximab impacts leukocyte RNA expression and serum inflammatory proteins Supplementary material Supplementary table 1. Results of the serum proteins analysis Protein Infliximab treated patients Prednisolone treated patients Fold change (mean) False discovery rate Fold change (mean) False discovery rate Caspase 8 (CASP-8) -1.19 0.076 0.90 0.410 C-C motif chemokine 23 (CCL23) -0.83 0.076 -0.34 0.350 C-C motif chemokine 4 (CCL4) -1.43 0.076 -0.45 0.635 Natural killer cell receptor 2B4 (CD244) -0.49 0.076 -0.24 0.410 CD40L receptor (CD40) -0.44 0.076 0.25 0.350 T-cell surface glycoprotein CD5 (CD5) -0.54 0.076 -0.32 0.410 CUB domain-containing protein 1 (CDCP1) -0.97 0.076 -0.26 0.708 C-X-C motif chemokine 1 (CXCL1) -0.82 0.076 -0.21 0.410 C-X-C motif chemokine 10 (CXCL10) -1.68 0.076 -0.01 0.903 C-X-C motif chemokine 11 (CXCL11) -2.22 0.076 -0.60 0.635 C-X-C motif chemokine 5 (CXCL5) -0.45 0.076 -0.48 0.350 C-X-C motif chemokine 9 (CXCL9) -2.37 0.076 -0.67 0.531 Protein S100A12 (EN-RAGE) -1.60 0.076 -0.21 0.799 Hepatocyte growth factor (HGF) -1.67 0.076 -0.44 0.350 Interferon gamma (IFN-gamma) -1.71 0.076 -0.30 0.635 Interleukin-12 subunit beta (IL-12B) -0.68 0.076 -0.52 0.410 Interleukin-18 (IL-18) -1.32 0.076 -0.17 0.635 Interleukin-18 receptor 1 (IL-18R1) -0.74 0.076 -0.12 0.799 Interleukin-6 (IL-6) -2.51 0.076 -0.72 0.350 Interleukin-7 (IL-7) -1.11 0.076 -0.68 0.350 Interleukin-8 (IL-8) -3.02 0.076 -0.01 0.708 Latency-associated peptide transforming growth factor beta 1 (LAP TGF-beta-1) -0.69 0.076 -0.34 0.410 Leukemia inhibitory factor receptor (LIF-R) -0.36 0.076 -0.13 0.708 Monocyte chemotactic protein 3 (MCP-3) -2.12 0.076 -0.28 0.531 Macrophage inflammatory protein 1-alpha (MIP-1 alpha) -2.17 0.076 -0.61 0.350 Matrix metalloproteinase-1 (MMP-1) -0.90 0.076 -0.40 0.531 Osteoprotegerin (OPG) -0.60 0.076 -0.06 0.903 Oncostatin-M (OSM) -2.91 0.076 -0.86 0.350 Programmed cell death 1 ligand 1 (PD-L1) -0.65 0.076 -0.23 0.350