Marjon Borgert

147 Implementation of care bundles in ICUs Malouf Todaro et al, 2013 Lawrence et al, 2012 Morris et al, 2011 Rello et al, 2013 Bloos et al, 2009 Hawe et al, 2009 Hatler et al, 2006 Youngquist et al, 2007 DePalo et al, 2010 Bukhari et al, 2012 Marra, 2009/Caserta, 2012 Al-Tawfiq et al, 2010 Miller et al, 2010 Zaydfudim et al, 2009 Bonello et al, 2008 Esmail et al, 2008 Jimenez et al, 2009 Elevation of the head of the bed (HOB) Daily sedation vacation Assessment of readiness to extubate Daily oral care Deep Venous Thrombosis prophylaxis Peptic ulcer disease prophylaxis Hand hygiene Intra cuff pressure Tubing management Subglottic suctioning Lung protective ventilation in patients with ALI Preferentialuse of oral vs nasal tubes for access to the trachea or stomach Spontaneous breathing trials Crunden et al, 2005 Berenholtz et al, 2011 Dubose et al, 2008 Berenholtz et al, 2004 x Daily sedation vacation and assessment of readiness to extubate Dental care x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x Ventilator bundle Helmick et al., 2014 x x x x x x Eom et al., 2014 x x x x Hamishehkar et al. 2014 x x x x Lim et al., 2013 x x x x x Mukhtar et al. 2014 x x x x x Al-Thaqafy et al., 2014 x x x x x Continuous aspiration of subglottic secretions (CASS) x x Maintain endotracheal cuff pressure (ETCP) x Use of a closed suction system x Use of a endotracheal tube with a separate dorsal lumen x Spontaneous breathing trial x Appropriate use / no use steroids Appropriate use / no use Xigris Maintain adequate glycemic control Low tidal volume Appropriate management of inspiratory plateau pressures (IPP) x x x x x x x x x x x x x x x x x x x x x x Serum lactate measured Blood cultures obtained prior to antibiotic administration Improve time to broad spectrum antibiotics Intravenous fluids delivered Maintain adequate central venous pressure Apply vasopressors for ongoing hypotension Maintain adequate central venous oxygen saturation Achieve and maintain mean arterial pressure ≥65 mmHg Blood pressure ≥90 mmHg in case of hypotension Fluids resuscitation / vasopressors (if appropriate) x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x Memon et al, 2012 Laguna Perez et al, 2012 Guiliano et al, 2011 Kim et al, 2012 Silverman et al, 2011, Sepsis bundle Ferrer et al. 2008 Schramm et al, 2011 Lefrant et al, 2010, Sepsis bundle Castellanos-Ortega et al, 2010 ^eƉsis resuscitation ďundle x x x x x x ^eƉsis ŵanageŵent ďundle Sepsis bundle

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