Marjon Borgert

149 Implementation of care bundles in ICUs Figure S1 shows that overall, there is no relation between the compliance level and the number of implementation strategies used ( r = 0.118, 95% CI. -0.331 to 0.523, p = 0.612), neither for each bundle separately: central line bundle: r = -0.155, 95% CI. -0.859 to 0.751, p = 0.769; ventilator bundle: r = 0.230, 95% CI.-0.467 to 0.751, p = 0.522; sepsis bundle: ρ = -0.112, p = 0.858. ρ = 0.14 0 10 20 30 40 50 60 70 80 90 100 0 1 2 3 4 5 6 7 8 9 10 11 Number of bundle elements Level of compliance in % Overall r = 0.388 0 10 20 30 40 50 60 70 80 90 100 0 1 2 3 4 5 6 7 8 9 10 11 Number of bundle elements Level of compliance in % Central line bundle r = 0.016 0 10 20 30 40 50 60 70 80 90 100 0 1 2 3 4 5 6 7 8 9 10 11 Number of bundle elements Level of compliance in % Ventilator bundle ρ = 0.527 0 10 20 30 40 50 60 70 80 90 100 0 1 2 3 4 5 6 7 8 9 10 11 Number of bundle elements Level of compliance in % Sepsis bundle Number of elements: Pre/post design & compliance calculated by AON−approach Figure S2. Number of bundle elements and compliance levels Overall, there is no relation between the number of bundle elements and the level of compliance (ρ = 0.140, p = 0.545), neither for each bundle separately: central line bundle: r = 0.388, 95% CI. -0.618 to 0.912, p = 0.447; ventilator bundle: r = 0.016, 95% CI.-0.620 to 0.639, p = 0.965; sepsis bundle: ρ = 0.527, p = 0.362.