Marjon Borgert

151 Implementation of care bundles in ICUs Subset 2: In the second subset, studies are included when prospective cohort designs were used, methodological quality scored ‘fair’ or ‘good’, and when compliance was calculated by using the all-or-none approach. The blue bar within the gures represents the 95% compliance level, thus the level of compliance which should have been achieved. Figures S4 to S6: • Overall, 10 studies are included in this subset, describing the compliance of 12 care bundles. • Central line bundle: 1 study included, describing the compliance of 2 care bundles • Ventilator bundle: 5 studies included, describing 5 care bundles • Sepsis bundle: 4 studies included, describing 6 care bundles. ρ = 0.539 0 10 20 30 40 50 60 70 80 90 100 0 1 2 3 4 5 6 7 8 9 10 Number of implementation strategies Level of compliance in % Overall 0 10 20 30 40 50 60 70 80 90 100 0 1 2 3 4 5 6 7 8 9 10 Number of implementation strategies Level of compliance in % Central line bundle ρ = − 0.154 0 10 20 30 40 50 60 70 80 90 100 0 1 2 3 4 5 6 7 8 9 10 Number of implementation strategies Level of compliance in % Ventilator bundle r = 0.195 0 10 20 30 40 50 60 70 80 90 100 0 1 2 3 4 5 6 7 8 9 10 Number of implementation strategies Level of compliance in % Sepsis bundle Number of strategies: Prospective cohort & compliance calculated by AON−approach Figure S4. Number of implementation strategies and compliance levels